What is Cannabidiol (CBD)?
CBD is one of sixty and one the most abundant compounds found in the plant species Cannabis. THC is one of the other most abundant compounds found in cannabis and is the compound that gets one “high”. Both compounds vary in concentration, depending on the plant variety, (ie. Marijuana plant and Hemp plant). Marijuana plants have a higher concentration of THC and a lower concentration of CBD (varies) but is not legal in all states/countries. Hemp plants contain a higher level of CBD and virtually no THC and is legal in 50 states.
How Does CBD work?
“Endocannabinoid System (ECS) is a group of endogenous cannabinoid receptors located in the mammalian brain and throughout the central peripheral nervous systems consisting of neuromodulatroy lipids and their receptors”. The ECS is involved in almost every system in your body (cardiovascular, digestion, relaxation and even cognitive and memory function) and your pet (and other mammals) have the same cannabinoid receptors in the ECS as humans. Within the ECS the brain and immune system produce cannabinoids, which bind to the body’s receptors known as CB1 and CB2.
Two primary endocannabinoid receptors that have been identified are CB1 (found in nervous system, connective tissues, glands and organs) and CB2 (found mainly in the immune system), and are responsible for controlling the ECS. CBD works by “activating” the CB1 and CB2 receptors and promoting the body’s natural healing mechanism.
Medical read: Cannabinoids as novel anti-inflammatory drugs (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/)
|Antiemetic||Reduces nausea and vomiting|
|Anticonvulsant||Suppresses sizure activity|
|Antipsychotic||Combats psychosis disorders|
|Anti-inflammatory||Combats inflammatory disorders|
|Anti-Oxidant||Combats neurodegenerative disorders|
|Anti-tumoral/Anti-Cancer||Combats tumor and cancer cells|
|Antiolytic/Anti-depressant||Combats anxiety and depression disorders|
The 1980 Study That Was Ignored
The short(er): “In phase 2 of the study, 15 patients suffering from secondary generalized epilepsy with temporal focus were randomly divided into two groups. Each patient received, in a double-blind procedure, 200-300 mg daily of CBD or placebo. The drugs were administered for along as 4 1/2 months. Clinical and laboratory examinations, EEG and ECG were performed at 15- or 30-day intervals. Throughout the experiment the patients continued to take the antiepileptic drugs prescribed before the experiment, although these drugs no longer controlled the signs of the disease. All patients and volunteers tolerated CBD very well and no signs of toxicity or serious side effects were detected on examination. 4 of the 8 CBD subjects remained almost free of convulsive crises throughout the experiment and 3 other patients demonstrated partial improvement in their clinical condition. CBD was ineffective in 1 patient.” – https://www.ncbi.nlm.nih.gov/pubmed/7413719
After looking at a few different options for a CBD supplement, we settled with PetReleaf for two main reasons.
Quality and Potency
The hemp plants used are organically grown (non-GMO) on family farms in France and Hungary and are contractually obligated to guarantee potency and consistency.
The market recently has been flooded with lower quality Chinese/Russian sourced hemp. A lot of these hemp plants are grown for one purpose – to “clean” toxic and radioactive soils (Chernobyl phytoremediation project)! “Your plants are what your plants eat” and hence a lot of these plants will carry toxic/radioactive isotopes.
The extraction process used by PetReleaf does not utilize any harmful chemicals or solvents (butane or hexane) but rather a more expensive process of CO2 (carbon dioxide) extraction is used. CO2 under high pressure and extremely low temperature isolates, preserves and maintains the purity of the medicinal oil. It is an expensive and difficult process (to learn) but the end result is a safe, potent and chlorophyll free oil. Other safe processes include: Ethanol but the extraction method destroys the plant waxes which have possible health benefits and Olive oil, but the method does not result in a high potent oil and is perishable if not stored in a cool dark place.
All products are tested by an independent 3rd party laboratory to ensure 100% safety and efficiency.
The PetReleaf Products
CBD Hemp Oil – Pet Releaf CBD hemp oil is a more concentrated form of CBD oil and intended for those pets that need a higher dosage.
100mg Hemp Oil Dosage
Cat Weight Dosage
Up to 15lbs/7kg 1/2 dropper morning, 1/2 dropper afternoon
over 15lb/7kg 3/4 dropper morning, 3/4 dropper afternoon
Dog Weight Dosage morning Afternoon
Up to 25lbs/11kg 1 dropper 1/2 dropper
25 – 50lb/11 – 23kg 1 1/2 dropper 1 dropper
50 – 75lb/23 – 34kg 2 droppers 1 1/2 droppers
over 75lb/34kg 2 droppers 2 droppers
300mg Hemp Oil Dosage
Dog Weight Usage Recommendation
- Up to 25 lbs 1/2 dropper per day
- 25-50 lbs 1 dropper per day
- 50-75 lbs 1 1/2 droppers per day
- 75-100 lbs 2 droppers per day
- Over 100 lbs 2 1/2 droppers per day
* To maximize the benefits of the CBD hemp oil, offer it on an empty stomach. If your cat does not like to accept things from a dropper, they recommend putting the oil onto a small treat, such as one of their Edibits.
*If your dog needs more of the CBD’s health benefits, it is safe to increase the dosage beyond these recommendations. If you choose to increase dosage, they recommend you do so slowly over time (10 days to 2 weeks).
Edibite & Large Breed Edibite Treats
- Flavors carried: Peanut Butter Banana & Blueberry Cranberry
- CBD treats specially formulated for dogs
- Each Edibite has 1.5 MG of CBD and the Large Breed Edibite treat has 3 MG of CBD.
- Organic, human grade and whole food ingredients
- Created with veterinarians and their master chef
- Made in the USA in small batches
Customer Reviews and Testimonials
“We can really attest to this product because we have tried everything and have had no answers to her endless pain from epilepsy. This product really works! We cannot thank this company enough for their amazing products!” – Lydia, Doggy Mom to Epileptic Pug, JujuBee
“Our friend has been using your drops on her older dog who is literally about to die. She said he had immediate improvement overnight and was able to move more freely and seemed in less pain the following day!! She is a believer!” – 2nd Fetch
“I got this for my 8-year-old boxer. He has significant arthritis in his back knees, as well as spondylosis in all but 3 spinal vertebrae. I didn’t want to put him on long term pain meds knowing what affects that would have on his liver. After some research, I thought I’d give this a try. Within 3 days of taking this, he’s like a puppy again! Running, jumping, chasing rabbits, nothing’s stopping him! Absolutely will be a return customer!!!” – Joanna